Lycopene has been used as an immune stimulant in a variety of cancers. Blood levels of lycopene were found to be inversely related to the risk of developing endometrial cancer in a group of females. Additionally, cell studies show that lycopene can inhibit cancer progression in estrogen affected cancer cells, such as the endometrial cells.
Omega-3 fatty acids, DHA and EPA, have been shown to exert numerous anti-cancer effects on breast cancer cells. Human studies are limited on endometrial cancer but one did recently establish that dietary PUFA and DHA inhibited endometrial cancer cell proliferation, colony formation, and migration, and promoted cell-programmed death (apoptosis) in animal and in-vitro models. Additionally, GLA, another omega-3, helps to maintain balance in the fatty acids and enhances the anti-inflammatory effect.,
Suggested dose: 2-3 grams combined EPA & DHA per day, with at least 1-2 grams of a GLA source.
Used as an adjunctive to chemotherapy for lung cancer patients, cell-based studies have demonstrated that Scutellaria inhibited NFκB formation, which could be beneficial to slow endometrial cancer.
Suggested dose: Dried herb: 1 to 2 grams 3 times per day; Tea: 240 mL 3 times per day or as a tincture: 2 to 4 mL 3 times per day.
Vitamin D levels are associated with the risk of most hormone cancers, including endometrial cancers. Studies on human cells demonstrate that vitamin D protects against endometrial cancer progression.,Individuals with a history of lymphoma should also monitor 1,25 dihydroxy-vitamin D levels, as rapid conversion to this active form has been observed.
Suggested dose is that sufficient to raise vitamin D blood levels to >40 ng/mL, which may require 5000 IU per day or more.