Catechins, antioxidants found in green tea, particularly EGCG (epigallocatechin-3-gallate), are known to have many anti-tumor affects. In human adult T-cell leukemia cells, ECGC reduced cancer cell proliferation. In animal studies of leukemia cells, a similar mechanism of tumor cell death was found.
Olive leaf contains the antioxidants oleuropein and hydroxytyrosol, which are believed to have anti-cancer affects. Olive leaf extracts induced apoptosis (programmed cell death) as well as induction of differentiation (moving them toward a more normal phenotype) of human leukemia cells.,
Suggested dose: 250 to 500 mg of a standardized extract, 1-3 times per day.
Grape seed extract used on leukemia cell lines decreased uncontrolled cell proliferation and survival and increase cell death in leukemia cells., Other studies indicate that the antioxidant in grape seeds called proanthocyanidins are likely to induce monocytic differentiation in leukemia cells (which prevents proliferation).,
Human trials have shown that low levels of vitamin D are related to a higher risk of developing leukemia and also with a worsening prognosis following a diagnosis of AML. Increased vitamin D level was associated with higher survival rate in elderly patients with acute myeloid leukemia. Individuals with a history of lymphoma should also monitor 1,25 dihydroxy-vitamin D levels, as rapid conversion to this active form has been observed in patients with lymphoma.
Suggested dose is that sufficient to raise vitamin D blood levels to >40 ng/mL, which may require 5000 IU per day or more.