BioActive Folate & Vitamin B12

What Is BioActive Folate & Vitamin B12?

BioActive Folate & Vitamin B12 supports the heart, brain, GI tract and more because its capsules contain the clinically studied, biologically active forms of folate (as 5-methyltetrahydrofolate) and vitamin B12 (as methylcobalamin).

BioActive Folate & Vitamin B12 capsules use clinically studied forms of folate and vitamin B12 to maximize benefits.

BioActive Folate & Vitamin B12 Benefits

• Supports heart health & already normal homocysteine levels
• Promotes nerve cell growth, brain health, cognition & metabolism
• Helps maintain a healthy GI tract
• Supports a healthy immune system & nervous system function
• Helps maintain production of red blood cells within normal range

The Variety of Vitamin B

The vitamin B family is much more complex than most people realize, and it also offers numerous health benefits. With this in mind, Life Extension formulated BioActive Folate & Vitamin B12 with some of the most biologically active forms of folate and vitamin B12 to maximize benefits for the heart, brain and GI tract.

Note: Healthful diets with adequate folate may reduce a woman’s risk of having a child with a brain or spinal cord defect. Women of childbearing age should consume 600 - 800 mcg of folate daily.

More facts about BioActive Folate & Vitamin B12

BioActive Folate & Vitamin B12 capsules contain the biologically active forms of folate (as 5-methyltetrahydrofolate) and vitamin B12 (as methylcobalamin).

5-methyltetrahydrofolate (5-MTHF) is the metabolically active form of folic acid. It’s the only form of folate used directly by the body and does not require metabolic conversion or activation. 5-MTHF is up to seven times more bioavailable than folic acid.¹ 5-MTHF can cross the blood-brain barrier, which allows 5-MTHF specifically to benefit the neurological system.

Methylcobalamin is the bioactive form of B12 that is readily utilized in the body and central nervous system.

What Folate Does for the Body

Folate is a member of the B-complex family. It is found in abundance in leafy green vegetables. Folate participates in an enzymatic reaction that synthesizes DNA needed for cell growth and new cell formation, and it helps convert vitamin B12 to one of its bioactive forms.

Folate provides many health benefits, including helping to promote healthy DNA function, maintaining already normal homocysteine levels for heart health, promoting healthier skin, and helping to maintain a healthy GI tract and immune system. It also maintains healthy endothelial function and may improve mild memory loss associated with aging.^2-6

Optimal levels of folate are necessary for healthy cell division and protein synthesis and are especially important for the maintenance of a healthy GI tract. Chronic use of medications such as aspirin in therapeutic doses and antacids can interfere with the metabolism of folate.

The Impact of Vitamin B12

Vitamin B12 is found in foods of animal origin, including dairy products and eggs. Thus, vegetarians are more susceptible to a dietary deficiency of this important nutrient. With aging, absorption of vitamin B12 from dietary sources typically declines.⁷

Benefits of vitamin B12 include supporting brain health and cognition, and supporting heart health by regenerating the amino acid methionine, which helps maintain healthy homocysteine levels. B12 also helps enhance methylation and promote nerve cell growth, brain health, cognition and metabolism. And when combined with folate, it helps maintain the production of red blood cells (erythropoiesis) within normal range.⁷

1. Am J Clin Nutr. 2006;84(1):156-61.
2. Linus Pauling Institute. Folate. Accessed 6/11/2019. https://lpi.oregonstate.edu/mic/vitamins/folate
3. Subcell Biochem. 2012;56:181-97.
4. Br J Cancer. 2009;100(2):233-9.
5. Clin Immunol. 2009;133(3):287-94.
6. Proc Natl Acad Sci U S A. 2013;110(23):9523-8.
7. Linus Pauling Institute. Vitamin B12. Accessed 6/11/19. https://lpi.oregonstate.edu/mic/vitamins/vitamin-B12

Dosage and Use

Take one (1) capsule daily, or as recommended by a healthcare practitioner.

Warnings

KEEP OUT OF REACH OF CHILDREN
DO NOT EXCEED RECOMMENDED DOSE
Do not purchase if outer seal is broken or damaged.
When using nutritional supplements, please consult with your physician if you are undergoing treatment for a medical condition or if you are pregnant or lactating.