Melatonin 300 mcg

What Is Melatonin?

Melatonin is a hormone derived from the amino acid tryptophan. Primarily synthesized in your pineal gland, melatonin is released mostly at night to make falling asleep easier. In addition to healthy sleep support, melatonin can help inhibit oxidative stress to promote healthy brain function, immune health and more.

Melatonin increases the speed of falling asleep and adds to quality of sleep. It also offers powerful protection against free radicals.

Melatonin Benefits

• Promotes restful sleep
• Helps support circadian rhythms & immune function
• Promotes cellular DNA health
• Helps inhibit oxidative stress & protect against free radicals

For occasional sleeplessness.

Melatonin: Just to Support Sleep?

People take melatonin to encourage optimal sleep, but melatonin also supports other important bodily systems: it helps inhibit oxidative stress, promotes immune health and supports cognitive function. So, melatonin isn’t just for restful sleep, but overall well-being.

Melatonin increases the speed of falling asleep and adds to the quality of sleep. It also offers strong protection against free radicals and supports healthy DNA.

Melatonin is a hormone derived from the amino acid tryptophan. It's primarily synthesized by your pineal gland in your brain and released mostly at night to make falling asleep easier.

In addition to healthy sleep support, melatonin offers protection against free radicals and has been shown to support immune health, healthy brain function and more.

Melatonin and sleep

A good night's sleep is crucial for overall health and well-being. But many people experience difficulty falling asleep and staying asleep. Healthy sleep patterns are governed by your body's circadian rhythms, and melatonin helps keep your circadian rhythms in tune.¹

But melatonin release declines with age, and can be affected by jet lag, shift work and more.^2-5 Melatonin promotes healthy sleep/wake patterns and encourages the onset, duration and quality of sleep.^6,7

Melatonin and oxidation

Melatonin also offers strong protection against oxidative stress. Melatonin is especially important for healthy cellular DNA and mitochondria support because it helps inhibit oxidative damage by directly scavenging free radicals.^8-10 Melatonin does so more effectively than many other antioxidants. ^11,12

Melatonin and immune health

Melatonin has a beneficial impact on the immune system.¹³ It activates T-helper cells, which trigger other immune cells, boosting immune system response to foreign molecules.¹⁴

Melatonin and cognitive health

Age-related cognitive decline may be directly correlated to melatonin levels.¹⁵ Melatonin supplementation can help support the brain's normal protection against free radicals and may help support cognitive function.^15,16

Why Should I Supplement With Melatonin?

"It's estimated that 50 to 70 million American adults have difficulty sleeping. Lack of quality restful sleep can impact your cognitive health, metabolism and much more.

Whether you need help falling asleep or staying asleep, Life Extension has a Melatonin product that will help your body get the rest it needs."

Dr. Michael A. Smith, MD: Director of Education and Spokesperson for Life Extension.

1. Curr Top Med Chem. 2002;2(2):199-209.
2. J Pineal Res. 2011;50(1):1-7.
3. Bull Acad Natl Med. 2011;195(7):1527-46; discussion 1547-9.
4. J Pineal Res. 1986;3(4):379-88.
5. Exp Gerontol. 2001;36(7):1083-100.
6. J Sleep Res. 2007;16(4):372-80.
7. Neurological Research. 2017;39(6):559-565.
8. J Endocrinol Invest. 2006;29(3):281-7.
9. Interdiscip Toxicol. 2008;1(2):137-49.
10. Molecules. 2018;23(3):530.
11. Aging (Milano). 1995;7(5):340-51.
12. Molecules. 2015;20(10):18886-906.
13. Int J Mol Sci. 2013;14(4):8638-83.
14. Endocrine. 2005;27(2):189-200.
15. J Pineal Res. 2012;52(4):365-75.
16. Neurotox Res. 2013;23(3):267-300.

Dosage and Use

• Take one (1) capsule 30 to 60 minutes before bedtime, or as recommended by a healthcare practitioner.
• Melatonin is naturally secreted from the pineal gland at night, and should be taken at night for optimal results.

Caution

Do not consume alcohol, drive or operate machinery after taking this product.
Warnings

KEEP OUT OF REACH OF CHILDREN
DO NOT EXCEED RECOMMENDED DOSE
Do not purchase if outer seal is broken or damaged.
When using nutritional supplements, please consult with your physician if you are undergoing treatment for a medical condition or if you are pregnant or lactating.