Lipid Support Complex

• Supports hepatic fat metabolism^‡
• Reduces oxidative stress^‡
• Supports vascular health^‡
• Promotes healthy uric acid levels^‡

Indications

• Ages 18 and up
• Patients seeking support for healthy liver fat metabolism^‡
• Patients seeking support for healthy uric acid levels or oxidative stress^‡

Suggested Use

As a dietary supplement, take 2 capsules daily with meals, or as directed by a health care professional.

Verifiable Science

In a randomized, double-blind, placebo-controlled clinical study involving 102 subjects, BergacynFF^® (600 mg/day for 12 weeks) provided significant support for healthy liver fat metabolism, as assessed by CAP scores.² In another randomized, double-blind, placebo-controlled study of 80 subjects, BergacynFF^® (600 mg/day) significantly improved markers of oxidative stress after 16 weeks, demonstrating reductions in circulating malondialdehyde (MDA) and increases in glutathione peroxidase (GPx) and superoxide dismutase (SOD). Supplementation also supported vascular endothelial function.⁴ This formula additionally provides berberine, an alkaloid shown in vitro to moderate lipid accumulation in liver cells.^5-8 Preclinical models indicate that berberine activates hepatic AMP kinase (AMPK) and sirtuin 1 (SIRT1), key regulators involved in supporting fat utilization and moderating fat synthesis in the liver.^7,8-10†

References

1. Ferro Y, et al. Medicina (Kaunas). 2022 Nov 26;58(12):1728.
2. Ferro Y, et al. Front Endocrinol (Lausanne). 2020 Aug 11;11:494.
3. Parafati M, et al. J Nutr Biochem. 2015;26:938–48.
4. Musolino V, et al. J Tradit Complement Med. 2020 Feb 8;10(3):268-274.
5. Xu X, et al. FASEB J. 2019 Jun;33(6):7289-7300.
6. Ionita-Radu F, et al. Int J Mol Sci. 2024 Apr 10;25(8):4201.
7. Yu M, et al. Int J Biol Sci. 2021 Apr 12;17(7):1693-1707.
8. Zhu X, et al. Free Radic Biol Med. 2019 Sep;141:192-204.
9. Smith BK, et al. Am J Physiol Endocrinol Metab. 2016 Oct 1;311(4):E730-E740.
10. Tian C, et al. Pharmacol Res. 2024 May;203:107155.

Warning

Not to be taken by pregnant or lactating women. If you have any health condition or are taking any medication, consult your health professional before use.

Storage

Store in a cool, dry place.

Source

Bergamot orange extract is derived from Citrus bergamia fruitt
Cardoon artichoke extract is derived from Cynara cardunculus leaf
Ascorbyl palmitate is derived from corn dextrose fermentation and palm oil
Tri-magnesium citrate is derived from elemental ore and non-GMO glucose fermentation from non-GMO maize, molasses, and sugar beet or sugar cane
Hypo-allergenic plant fiber is derived from pine cellulose