Super Ubiquinol CoQ10 with PQQ

What Is Super Ubiquinol CoQ10 with PQQ?

CoQ10 is essential for cellular energy production, as are your cellular mitochondria. But CoQ10 levels decline with age, along with your number of functioning mitochondria. This is why we’ve created our best-in-class Super Ubiquinol CoQ10 with PQQ: a formula designed to support cellular energy production and promote new mitochondrial growth at the same time.

The cells in your heart, brain and other vital organs need mitochondria, and those mitochondria need CoQ10. This formula supports both!

Super Ubiquinol CoQ10 with PQQ Benefits

• Ubiquinol absorbs up to 8x better than standard CoQ10
• PQQ encourages the growth of new mitochondria
• Shilajit complements CoQ10’s cellular energy benefits

What is our ubiquinol CoQ10?

Ubiquinol is a form of CoQ10 that absorbs up to 8 times better than the traditional ubiquinone form, enhancing its health benefits.

Why did we add PQQ?

PQQ is a powerful nutrient. It promotes the production of new mitochondria, helps protect mitochondrial DNA and helps inhibit oxidative stress at the cellular level.

CoQ10 for heart health & cellular energy

CoQ10 (or coenzyme Q10) is an essential nutrient your body requires for healthy mitochondrial function, a process that produces body energy at the cellular level.^1-3 Because of this, it makes sense that CoQ10 is concentrated in organs with high-energy demands such as your brain, liver, kidneys and the heart.^2-6

CoQ10 also has powerful antioxidant properties, protecting cell membranes, important proteins and mitochondrial DNA from oxidative stress.^7,8 Unfortunately, CoQ10 levels in the body decrease over time.^9,10

Improved bioavailability: ubiquinol

The traditional ubiquinone form of CoQ10 is difficult for the body to absorb.¹¹ That's why Life Extension® offers a highly bioavailable form of ubiquinol CoQ10 in a patented delivery system shown to absorb up to 8 times better than ubiquinone.^12,13 In people taking this form of ubiquinol, high levels of plasma CoQ10 were achieved in only four weeks.¹⁴

Shilajit enhances CoQ10 effectiveness

Shilajit is a nutrient discovered in the Himalayas. In preclinical models, shilajit has been shown to promote mitochondrial energy production and increase adenosine triphosphate (ATP), which is the main source of cellular energy.^15,16 The combination of CoQ10 and shilajit produced a 56% increase in cellular energy production in the brain—45% better than CoQ10 alone. Muscle tissue saw a 144% increase in ATP, more than 50% better than with CoQ10 by itself.¹⁵

CoQ10 and aging

With increasing age, in addition to declining CoQ10 levels, the body’s ability to convert ubiquinone into active ubiquinol declines.¹⁷ In a pre-clinical model, ubiquinol was up to 40% more effective at slowing measurements of aging compared with ubiquinone.¹⁸ 

PQQ promotes growth of new mitochondria

PQQ (pyrroloquinoline quinone) is a nutrient that promotes the production of new mitochondria. In fact, PQQ promotes youthful cellular function in three distinct ways:

• Promotes mitochondrial biogenesis. PQQ activates genes that promote the formation of fresh mitochondria. It also beneficially interacts with genes directly involved in mitochondrial health.¹⁹
• Mitochondrial support. PQQ’s antioxidant potency and favorable gene-expression profile act to support mitochondrial defense.²⁰
• Antioxidant power. PQQ is a potent antioxidant, and its molecular stability enables PQQ to facilitate thousands of antioxidant reactions in the mitochondria, without breaking down, for maximum antioxidant and bioenergetic support.²¹

1. Biochimica et Biophysica Acta (BBA) - Bioenergetics. 2016;1857(8):1073-1078.
2. J Am Coll Nutr. 2001;20(6):591-8.
3. Mitochondrion. 2007;7:S2-S7.
4. Curr Atheroscler Rep. 2018;20(6):29.
5. Clin Physiol. 1988;8(4):391-8.
6. Neuropsychiatric disease and treatment. 2009;5:597-610.
7. Mitochondrion. 2007;7:S41-S50.
8. Mol Biotechnol. 2007;37(1):31-7.
9. Front Physiol. 2018;9:44.
10. Mech Ageing Dev. 2010;131(4):225-35.
11. Recent Patents on Drug Delivery & Formulation. 2010;4(3):245-255.
12. Kaneka Corp. CoQ10 reducing activity in rats. Unpublished internal study data.
13. Exp Neurol. 2004;188(2):491-4.
14. Regul Toxicol Pharmacol. 2006;47(1):19-28.
15. Pharmacologyonline. 2009;1:817-25.
16. Journal of ethnopharmacology. 2012;143(1):91-99.
17. J Am Geriatr Soc. 2016;64(1):55-64.
18. Exp Gerontol. 2006;41(2):130-40.
19. Biochemistry. 2017;56(50):6615-6625.
20. J Nutr Biochem. 2013;24(12):2076-84.
21. Biochem Biophys Res Commun. 2007;363(2):257-62.

Dosage and Use

Take one (1) softgel daily with food, or as recommended by a healthcare practitioner.

Warnings

• KEEP OUT OF REACH OF CHILDREN
• DO NOT EXCEED RECOMMENDED DOSE
• Do not purchase if outer seal is broken or damaged.
• When using nutritional supplements, please consult with your physician if you are undergoing treatment for a medical condition or if you are pregnant or lactating.