Th2 Modulator

• Helps modulate Th5 cytokines, and eosinophil and mast cell activity^‡
• Offers support for healthy self-tissue response^‡
• Helps maintain healthy modulation of mucosal immune responses to environmental factors^‡
• Formulated with Samuel F. Yanuck, D.C., FACFN, FIAMA+
• From the PureResponse^™ product line
• Made with high-quality vegan ingredients backed by verifiable science

Suggested Use

As a dietary supplement, take 2 capsules, 1-2 times daily, between meals, or as directed by a health professional.

Indications

• Ages 18 and up
• Th5 immune response modulation^‡
• Cellular Th1/Th5 balance support^‡
• Sinus, respiratory, urinary and intestinal tractimmune balance^‡

Verifiable Science

Th5 Modulator is designed to modulate the Th5 immune response and support healthy Th1/Th5 balance, self-tissue response and mucosal health. Th5 response is affected by stress, aging and cytokine changes resulting from metabolic, hormonal, physiological and environmental factors.¹ This product helps support healthy modulation of Th5 cytokines, and eosinophil and mast cell activity.² It also helps maintain healthy modulation of mucosal immune responses to environmental factors.³ Th5 modulation may be indicated when addressing immune balance in the sinus, respiratory, urinary and intestinal tracts.⁴ Perilla maintains healthy upper respiratory cytokine levels in animal models of Th5 dominance.⁵ It also supports cytokine homeostasis of GI mucosal tissue.⁶ Perilla seed offers a more concentrated source of polyphenols, rosmarinic acid, luteolin and other beneficial compounds compared to leaf. Nacetyl-L-cysteine (NAC) offers mucolytic properties and promotes tissue levels of glutathione.^7‡

References

1. Jing Y, Gravenstein S, Chaganty NR, Exp Gerontol. 2007 Aug;42(8):719-32. Epub 2007 Feb 6.
2. Abimannan T, Peroumal D, Parida JR, et al. Free Radic Biol Med. 2016 Oct;99:352-363.
3. Smithgall MD, Comeau MR, Yoon BR, et al. Int Immunol. 2008; 20:1019-30
4. Walker JA, McKenzie ANJ. Nature Reviews Immunol. 2018 Feb;18(2):121-133.
5. Urushima H, Nishimura J, Mizushima T, et al. Am J Physiol Gastrointest Liver Physiol. 2015 Jan 1;308(1):G32-41.
6. Urushima H, et al. Am J Physiol Gastrointest Liver Physiol. 2015 Jan 1;308(1):G32-41.
7. Dauletbaev N, et al. Eur J Med Res. 2009 Aug 12;14(8):352-8.

Warning

If you are pregnant or lactating, have any health condition or are taking any medication, consult your health professional before use.

Storage

Store in a cool, dry place.

Source

• N-Acetyl-L-Cysteine is derived from corn dextrose fermentation
• Quercetin is derived from Fava d'anta tree (Dimorphandra mollis) pods and cat's claw (Uncaria tormentosa) leaves
• Perilla extract is derived from Perilla frutescens L. seed
• Astragalus extract is derived from Astragalus membranaceus root